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Research
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PubMed COVID-19 Clinical Care

3201 - 3210 of 3573 results found

Evolution of the SARS-CoV-2 mutational spectrum

Date
Tuesday, April 11, 2023 - 4:00 AM
Description
SARS-CoV-2 evolves rapidly in part because of its high mutation rate. Here we examine whether this mutational process itself has changed during viral evolution. To do this, we quantify the relative rates of different types of single nucleotide

Exploring polyamine interactions and binding pockets in SARS-CoV-2 ORF3a

Date
Monday, April 10, 2023 - 4:00 AM
Description
Ongoing global pandemic caused by coronavirus (COVID-19) requires urgent development of vaccines, treatments, and diagnostic tools. Open reading frame 3a (ORF3a) from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered to be a